Tretinoin is a widely used topical preparation available in different dosage forms and strengths. Tretinoin 0.05% cream is one of the most popular dosage forms and has specific positioning in treating dermatological disorders. Tretinoin cream at strength of 0.025% is an excellent comedolytic agent while Tretinoin 0.05% cream effectively recovers the complications associated with photodamaged skin like wrinkle and hyperpigmentation. Thus it has created a great attention to the scholar regarding its skin rejuvenating effect. From clinical studies it has been established that Tretinoin 0.05% cream is safe for the long term use in the treatment of photodamaged skin.
Ultraviolet radiation exerts adverse effects on skin. It causes degradation of collagen and makes the skin surface rough. Tretinoin 0.05% cream diminishes the effect of ultraviolet radiation and helps in collagen formation. As a result it reduces wrinkle and hyperpigmentation in photodamaged skin. By eliminating dead cells from skin surface it also makes the skin smooth.
Like other strengths of Tretinoin cream, it has to apply once daily preferably at evening or at night time. Before applying the entire face has to wash properly with a non soap or a mild soap cleanser. If anyone uses make-up, then it has to remove completely before applying this cream. A thin layer of cream should be applied to the affected areas. Using too much or more than usual frequency dose not bring better result. Rather this may cause potential skin reactions. Application of moisturizer is recommended during using this preparation. Due to its irritation potential precaution needs to take to avoid sunlight exposure i.e, using sunscreen or protective clothing. Usually 6 to 8 weeks application is recommended. Also safety has established up to two years of application.
Another remarkable use of Tretinoin 0.05% cream is in hair regrowth treatment. In combination with topical Minoxidil it shows excellent effect on new hair growth. Tretinoin can control cellular and vascular proliferation. It increases the absorption of Minoxidil and ensures better result. Topical Minoxidil helps in growing hair primarily in the vertex of the scalp. It has lower effect on other scalp region. But combination of Minoxidil and Tretinoin 0.05% cream ensures hair growth from all regions of the scalp. Combination treatment also reduces the maintenance dose requirement and provides excellent result. This combination treatment can be continued for two years.
This preparation can not be applied in eyes or other mucous membrane. It is contraindicated in condition where the patient can not tolerate Tretinoin or any other ingredients of the formulation. Patient with family history of skin cancer should not use this preparation. It is also not recommend for pregnant and breast feeding mother.
If anyone applies other anti-acne products, it needs to tell the physician before using this cream. In such case physicians usually prefer using these preparations at two different times of the day. Preparation containing Benzoyl Peroxide can not be used at the same time due to the risk of developing skin reaction.
Tretinoin 0.05% cream is prescription only medicine and not for over the counter use. Depending on the skin conditions and severity of skin damage, dermatologists can suggest using it. Have to consult immediately with physician in case of excess irritation. Commonly seen adverse effects are redness at application site, dry skin, irritation and stinging. Even in case of applying large amount or unwanted skin fold application it is also recommended to take physician’s supervision. Tretinoin 0.05% cream can not be used in children. It can be used in adolescents or adult under defined skin problems.
Due to excellent efficacy of Tretinoin 0.05% cream in photodamaged skin it brings hope for a huge population. Application of this cream with proper manner and under the continuous supervision of physician can make its effect optimal.
“All About Tretinoin Cream”